Treatments
The Rigenera treatment is approved at the European Union level and is based on the science behind a project initiated by NATO – Science for Peace and Security Programme which aims to rapidly heal wounds caused by thermal or chemical burns such as those in the theater of war or following natural disasters.
It is an important moment in Regenerative Medicine in Romania because adult stem cell transplantation becomes accessible to all patients of Ortokinetic Medical Centers. Rigenera is a cell regeneration treatment that provides an enriched concentrate of stem cells in the affected area, with the aim of determining in particular the installation of tissue regeneration and healing processes.
By using stem cells harvested from healthy tissue and then applied to the affected area, rapid tissue regeneration is achieved.
In a single procedure, the patient becomes both the donor and the recipient of the selected stem cells, thus enriching the number of regenerative cells in the affected tissue.
1. Tissue collection
Under local anesthesia, a piece of tissue is harvested from the ear using a 2.5 mm biopsy punch.
2. Micro-graft preparation
The harvested tissue is processed and placed in the Rigenera unit, which for 1 minute will fragment the tissue and filter the resulting product at micron level.
3. Treatment application
The micrograft is collected with a syringe and then injected into the lesion.
The advantage of this innovative method is that the treatment is performed in a single surgical time, without the need for hospitalization, the patient being both donor and recipient of specialized progenitor cell micrografts.
The key to its success lies in its efficiency and simplicity of use and it is already being used in Europe, Asia (with high demand especially in Japan) and South America. The innovative treatment is the result of 15 years of research, with the method already being used in over 40 countries worldwide with proven results.
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Rigenera is a tissue fragmentation technology capable of obtaining tens of thousands of micrografts from any human tissue in minutes.
They can also be used intra-operatively by the surgeon to regenerate damaged tissue, such as skin, bone or cartilage.
The technology we’re talking about is found in a disposable medical device called the Rigeneracon – a sterile capsule inside which fragments of tissue harvested painlessly from the patient are placed and fragmented to obtain micrografts.
The latter have an average size of 50 microns and can be used by direct application in the area requiring regeneration.
Rigeneracon medical devices (class I) have a network of 100 hexagonal holes, each hole is delimited by 6 micro-blades designed for efficient sectioning of both hard and soft tissues.
Cell disaggregation of a tissue fragment (square mm is sufficient for regeneration of up to 200 square mm of tissue) is performed together with filtering that takes into account predefined dimensions, resulting in the micro-groove we want.
After a short time of cell disintegration (1-5 minutes depending on the type of tissue) the microbead concentrate is extracted from the device and is ready to be used, exactly in the right form to be introduced into the surfaces to be treated.
The founders of the Rigenera brand are doctors Antonio Graziano and Riccardo D’Aquino. They started clinical trials in 2006, and the first line of technical-surgical devices based on Rigenera technology was ready in 2013.
In Romania, at the time of launch, Ortokinetic Medical Centers are the only access to this innovative treatment for the specialties Orthopedics – Traumatology and Dermatology.
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